Michael Addition of Carbon and Nitrogen Nucleophiles with Chalcone Catalyzed by Semicarbazide
نویسندگان
چکیده
منابع مشابه
Primary Amino Acid Lithium Salt-Catalyzed Asymmetric Michael Addition of Carbon Nucleophiles to Enones
Asymmetric Michael addition of carbon nucleophiles, nitroalkanes and a β-ketoester, to enones was investigated by using a primary amino acid lithium salt as a catalyst.
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Synthetically versatile conjugate addition of a range of carbon, nitrogen, oxygen, sulfur and selenium nucleophiles to the highly functionalised 2-thio-3-chloroacrylamides is described. The stereochemical and synthetic features of this transformation are discussed in detail. In most instances, the nucleophile replaces the chloro substituent with retention of stereochemistry. With the oxygen nuc...
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ژورنال
عنوان ژورنال: Chinese Journal of Organic Chemistry
سال: 2014
ISSN: 0253-2786
DOI: 10.6023/cjoc201403034